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Hangzhou Fuluo Biological Technology Co.,Ltd

Products >> Rivastigmine Tartrate/nootropic@ycgmp.com

Rivastigmine Tartrate/nootropic@ycgmp.com

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Description
Product Name: Rivastigmine Tartrate/nootropic@ycgmp.com
Supply Ability: 500kg/month
Related proudcts
Specifications 99%
Price Term: CNF
Port of loading: HK/Shanghai/Shenzhen
Minimum Order 5g
Unit Price: $1

Rivastigmine Tartrate

Product Name: Rivastigmine Tartrate
Alias: Rivastigmine-d6 tartarate
CAS: 129101-54-8
MF: C18H28N2O8
MW: 400.4235
Purity: 99%
MP: 123-125°C
BP: 316.2°C at 760 mmHg
FP: 145°C
Grade: Pharmaceutical Grade
Appearance: White Powder

Rivastigmine Tartrate is a parasy***thomimetic or cholinergic agent for the treatment of mild to moderate dementia of the Alzheimer's type and dementia due to Parkinson's disease. The drug can be administered orally or via a transdermal patch; the latter form reduces the prevalence of side effects, which typically include nausea and vomiting.

Pharmacological Effects

Rivastigmine Tartrate is rivastigmine Alzheimer's disease drugs, rivastigmine is physostigmine derivative by Novartis for the first time successfully developed the trade name Exelon (exelon), a molecule with there carbamate structure, is a kind of amino acid of selective cerebral cholinesterase inhibitor, can also inhibit the acetylcholinesterase and butyrylcholinesterase, cholinergic neurons by delaying the release of acetylcholine degradation and energy promoting cholinergic nerve conduction, can improve cognitive function disorders mediated by cholinergic, thereby improving the cognitive function of Alzheimer's disease patients.

Rivastigmine Tartrate plasma protein binding is weak, easily through the blood-brain barrier, which has a high degree of brain selectivity. It not only selectively acts on the most easily affected cerebral cortex and hippocampus, but also preferentially inhibits the dominant subtype of AChE in the brain, resulting in a reduction in the efficacy of peripheral cholinergic side effects. Rivastigmine in vivo half-life is short and long duration of action. Unlike tacrine, this product in the hippocampus and cortex of G1 enzyme inhibitory effect is stronger. Clinic for the treatment of mild to moderate Alzheimer-type dementia, or Alzheimer's disease can be suspected Alzheimer's disease clinically.

Dosage

The dosage of Exelon to treat Alzheimer'

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Company: Hangzhou Fuluo Biological Technology Co.,Ltd
Contact: Ms. Cindy Lee
Address: 4#Xinfeng Road,Hongjie Street,Jianggan District
Postcode: 310017
Tel: 86-0571-87963072
Fax: 86-0571-87963072
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